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Pharmacological Inhibition of Dynamin II Reduces Constitutive Protein Secretion from Primary Human Macrophages
Dynamins are fission proteins that mediate endocytic and exocytic membrane events and are pharmacological therapeutic targets. These studies investigate whether dynamin II regulates constitutive protein secretion and show for the first time that pharmacological inhibition of dynamin decreases secret...
Autores principales: | Kockx, Maaike, Karunakaran, Denuja, Traini, Mathew, Xue, Jing, Huang, Kuan Yen, Nawara, Diana, Gaus, Katharina, Jessup, Wendy, Robinson, Phillip J., Kritharides, Leonard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210248/ https://www.ncbi.nlm.nih.gov/pubmed/25347775 http://dx.doi.org/10.1371/journal.pone.0111186 |
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