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Acinus integrates AKT1 and subapoptotic caspase activities to regulate basal autophagy

How cellular stresses up-regulate autophagy is not fully understood. One potential regulator is the Drosophila melanogaster protein Acinus (Acn), which is necessary for autophagy induction and triggers excess autophagy when overexpressed. We show that cell type–specific regulation of Acn depends on...

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Detalles Bibliográficos
Autores principales: Nandi, Nilay, Tyra, Lauren K., Stenesen, Drew, Krämer, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210446/
https://www.ncbi.nlm.nih.gov/pubmed/25332163
http://dx.doi.org/10.1083/jcb.201404028