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AAV2-mediated follistatin overexpression induces ovine primary myoblasts proliferation

BACKGROUND: Follistatin (FST) has been shown to bind to some TGF-β family members and can function as a potent myostatin (MSTN) antagonist. Recent studies have revealed that over-expression of FST by adeno-associated viruses increases muscle growth in mice, humans and nonhuman primates. In the prese...

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Detalles Bibliográficos
Autores principales: Nazari, Mahmood, Salabi, Fatemeh, Zhang, Li, Zhao, Fuping, Wei, Caihong, Du, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210504/
https://www.ncbi.nlm.nih.gov/pubmed/25330993
http://dx.doi.org/10.1186/s12896-014-0087-7