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Activation of Akt at T308 and S473 in alcohol, tobacco and HPV-induced HNSCC: is there evidence to support a prognostic or diagnostic role?

BACKGROUND: Tobacco, alcohol and HPV infection are associated with increased risk of HNSCC. However, little is known about the underlying signaling events influencing risk. We aimed to investigate the relationship between these risk factors and Akt phosphorylation, to determine prognostic value. MET...

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Detalles Bibliográficos
Autores principales: Islam, Mohammad R, Ellis, Ian R, Macluskey, Michaelina, Cochrane, Lynda, Jones, Sarah J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210546/
https://www.ncbi.nlm.nih.gov/pubmed/25352995
http://dx.doi.org/10.1186/2162-3619-3-25

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