FLRT Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development

FLRTs are broadly expressed proteins with the unique property of acting as homophilic cell adhesion molecules and as heterophilic repulsive ligands of Unc5/Netrin receptors. How these functions direct cell behavior and the molecular mechanisms involved remain largely unclear. Here we use X-ray cryst...

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Detalles Bibliográficos
Autores principales: Seiradake, Elena, del Toro, Daniel, Nagel, Daniel, Cop, Florian, Härtl, Ricarda, Ruff, Tobias, Seyit-Bremer, Gönül, Harlos, Karl, Border, Ellen Clare, Acker-Palmer, Amparo, Jones, E. Yvonne, Klein, Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210639/
https://www.ncbi.nlm.nih.gov/pubmed/25374360
http://dx.doi.org/10.1016/j.neuron.2014.10.008

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