The cardiac muscle duplex as a method to study myocardial heterogeneity

This paper reviews the development and application of paired muscle preparations, called duplex, for the investigation of mechanisms and consequences of intra-myocardial electro-mechanical heterogeneity. We illustrate the utility of the underlying combined experimental and computational approach for...

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Detalles Bibliográficos
Autores principales: Solovyova, O., Katsnelson, L.B., Konovalov, P.V., Kursanov, A.G., Vikulova, N.A., Kohl, P., Markhasin, V.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210666/
https://www.ncbi.nlm.nih.gov/pubmed/25106702
http://dx.doi.org/10.1016/j.pbiomolbio.2014.07.010
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author Solovyova, O.
Katsnelson, L.B.
Konovalov, P.V.
Kursanov, A.G.
Vikulova, N.A.
Kohl, P.
Markhasin, V.S.
author_facet Solovyova, O.
Katsnelson, L.B.
Konovalov, P.V.
Kursanov, A.G.
Vikulova, N.A.
Kohl, P.
Markhasin, V.S.
author_sort Solovyova, O.
collection PubMed
description This paper reviews the development and application of paired muscle preparations, called duplex, for the investigation of mechanisms and consequences of intra-myocardial electro-mechanical heterogeneity. We illustrate the utility of the underlying combined experimental and computational approach for conceptual development and integration of basic science insight with clinically relevant settings, using previously published and new data. Directions for further study are identified.
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spelling pubmed-42106662014-11-06 The cardiac muscle duplex as a method to study myocardial heterogeneity Solovyova, O. Katsnelson, L.B. Konovalov, P.V. Kursanov, A.G. Vikulova, N.A. Kohl, P. Markhasin, V.S. Prog Biophys Mol Biol Review This paper reviews the development and application of paired muscle preparations, called duplex, for the investigation of mechanisms and consequences of intra-myocardial electro-mechanical heterogeneity. We illustrate the utility of the underlying combined experimental and computational approach for conceptual development and integration of basic science insight with clinically relevant settings, using previously published and new data. Directions for further study are identified. Pergamon Press 2014-08 /pmc/articles/PMC4210666/ /pubmed/25106702 http://dx.doi.org/10.1016/j.pbiomolbio.2014.07.010 Text en © 2014 The Authors https://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Review
Solovyova, O.
Katsnelson, L.B.
Konovalov, P.V.
Kursanov, A.G.
Vikulova, N.A.
Kohl, P.
Markhasin, V.S.
The cardiac muscle duplex as a method to study myocardial heterogeneity
title The cardiac muscle duplex as a method to study myocardial heterogeneity
title_full The cardiac muscle duplex as a method to study myocardial heterogeneity
title_fullStr The cardiac muscle duplex as a method to study myocardial heterogeneity
title_full_unstemmed The cardiac muscle duplex as a method to study myocardial heterogeneity
title_short The cardiac muscle duplex as a method to study myocardial heterogeneity
title_sort cardiac muscle duplex as a method to study myocardial heterogeneity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210666/
https://www.ncbi.nlm.nih.gov/pubmed/25106702
http://dx.doi.org/10.1016/j.pbiomolbio.2014.07.010
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