Cargando…
13-Acetoxysarcocrassolide Induces Apoptosis on Human Gastric Carcinoma Cells Through Mitochondria-Related Apoptotic Pathways: p38/JNK Activation and PI3K/AKT Suppression
13-acetoxysarcocrassolide (13-AC), an active compound isolated from cultured Formosa soft coral Sarcophyton crassocaule, was found to possess anti-proliferative and apoptosis-inducing activities against AGS (human gastric adenocarcinoma cells) gastric carcinoma cells. The anti-tumor effects of 13-AC...
Autores principales: | Su, Ching-Chyuan, Chen, Jeff Yi-Fu, Din, Zhong-Hao, Su, Jui-Hsin, Yang, Zih-Yan, Chen, Yi-Jen, Wang, Robert Y.L., Wu, Yu-Jen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210900/ https://www.ncbi.nlm.nih.gov/pubmed/25342459 http://dx.doi.org/10.3390/md12105295 |
Ejemplares similares
-
An Investigation into the Cytotoxic Effects of 13-Acetoxysarcocrassolide from the Soft Coral Sarcophyton crassocaule on Bladder Cancer Cells
por: Su, Ching-Chyuan, et al.
Publicado: (2011) -
13-Acetoxysarcocrassolide induces apoptosis in human hepatocellular carcinoma cells through mitochondrial dysfunction and suppression of the PI3K/AKT/mTOR/p70S6K signalling pathway
por: Hsu, Chang-Min, et al.
Publicado: (2022) -
The Apoptotic Effect of Ursolic Acid on SK-Hep-1 Cells is Regulated by the PI3K/Akt, p38 and JNK MAPK Signaling Pathways
por: Chuang, Wan-Ling, et al.
Publicado: (2016) -
11-epi-Sinulariolide Acetate Reduces Cell Migration and Invasion of Human Hepatocellular Carcinoma by Reducing the Activation of ERK1/2, p38MAPK and FAK/PI3K/AKT/mTOR Signaling Pathways
por: Lin, Jen-Jie, et al.
Publicado: (2014) -
Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway
por: Wu, Yu-Jen, et al.
Publicado: (2019)