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Levels of Organochlorine Pesticides in Blood Plasma from Residents of Malaria-Endemic Communities in Chiapas, Mexico
Organochlorine (OC) pesticides have been extensively used for pest control in agriculture and against malaria vectors in the region of Soconusco, Chiapas, in southern Mexico. Our study aimed to identify whether the inhabitants of four Soconusco communities at different locations (i.e., altitudes) an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210989/ https://www.ncbi.nlm.nih.gov/pubmed/25310541 http://dx.doi.org/10.3390/ijerph111010444 |
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author | Ruiz-Suárez, Luz E. Castro-Chan, Ricardo A. Rivero-Pérez, Norma E. Trejo-Acevedo, Antonio Guillén-Navarro, Griselda K. Geissen, Violette Bello-Mendoza, Ricardo |
author_facet | Ruiz-Suárez, Luz E. Castro-Chan, Ricardo A. Rivero-Pérez, Norma E. Trejo-Acevedo, Antonio Guillén-Navarro, Griselda K. Geissen, Violette Bello-Mendoza, Ricardo |
author_sort | Ruiz-Suárez, Luz E. |
collection | PubMed |
description | Organochlorine (OC) pesticides have been extensively used for pest control in agriculture and against malaria vectors in the region of Soconusco, Chiapas, in southern Mexico. Our study aimed to identify whether the inhabitants of four Soconusco communities at different locations (i.e., altitudes) and with different history of use of OC pesticides, have been similarly exposed to residues of these pesticides. In particular, we analyzed the potential relationship between levels of OC pesticides in plasma and the age, gender, and residence of the study population (n = 60). We detected seven pesticides in total (γ-HCH, β-HCH, heptachlor, p,pʹ-DDE, p,p'-DDT, β-endosulfan, endrin aldehyde). Of these, p,pʹ-DDE and β-endosulfan were the most frequently found (in 98% and 38% of the samples, respectively). The low-altitude (<20 m above sea level; masl) and mid-altitude (520 masl) locations had the highest levels of p,pʹ-DDE, with geometric means of 50.6 µg/L and 44.46 µg/L, respectively. The oldest subjects (>60 years) had the highest p,pʹ-DDE level (56.94 ± 57.81 µg/L) of all age groups, while men had higher p,pʹ-DDE (34.00 ± 46.76 µg/L) than women. Our results demonstrate that residents of the Soconusco region are exposed to p,pʹ-DDE because of high exposure to DDT in the past and current environmental exposure to this DDT-breakdown product. |
format | Online Article Text |
id | pubmed-4210989 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-42109892014-10-28 Levels of Organochlorine Pesticides in Blood Plasma from Residents of Malaria-Endemic Communities in Chiapas, Mexico Ruiz-Suárez, Luz E. Castro-Chan, Ricardo A. Rivero-Pérez, Norma E. Trejo-Acevedo, Antonio Guillén-Navarro, Griselda K. Geissen, Violette Bello-Mendoza, Ricardo Int J Environ Res Public Health Article Organochlorine (OC) pesticides have been extensively used for pest control in agriculture and against malaria vectors in the region of Soconusco, Chiapas, in southern Mexico. Our study aimed to identify whether the inhabitants of four Soconusco communities at different locations (i.e., altitudes) and with different history of use of OC pesticides, have been similarly exposed to residues of these pesticides. In particular, we analyzed the potential relationship between levels of OC pesticides in plasma and the age, gender, and residence of the study population (n = 60). We detected seven pesticides in total (γ-HCH, β-HCH, heptachlor, p,pʹ-DDE, p,p'-DDT, β-endosulfan, endrin aldehyde). Of these, p,pʹ-DDE and β-endosulfan were the most frequently found (in 98% and 38% of the samples, respectively). The low-altitude (<20 m above sea level; masl) and mid-altitude (520 masl) locations had the highest levels of p,pʹ-DDE, with geometric means of 50.6 µg/L and 44.46 µg/L, respectively. The oldest subjects (>60 years) had the highest p,pʹ-DDE level (56.94 ± 57.81 µg/L) of all age groups, while men had higher p,pʹ-DDE (34.00 ± 46.76 µg/L) than women. Our results demonstrate that residents of the Soconusco region are exposed to p,pʹ-DDE because of high exposure to DDT in the past and current environmental exposure to this DDT-breakdown product. MDPI 2014-10-10 2014-10 /pmc/articles/PMC4210989/ /pubmed/25310541 http://dx.doi.org/10.3390/ijerph111010444 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ruiz-Suárez, Luz E. Castro-Chan, Ricardo A. Rivero-Pérez, Norma E. Trejo-Acevedo, Antonio Guillén-Navarro, Griselda K. Geissen, Violette Bello-Mendoza, Ricardo Levels of Organochlorine Pesticides in Blood Plasma from Residents of Malaria-Endemic Communities in Chiapas, Mexico |
title | Levels of Organochlorine Pesticides in Blood Plasma from Residents of Malaria-Endemic Communities in Chiapas, Mexico |
title_full | Levels of Organochlorine Pesticides in Blood Plasma from Residents of Malaria-Endemic Communities in Chiapas, Mexico |
title_fullStr | Levels of Organochlorine Pesticides in Blood Plasma from Residents of Malaria-Endemic Communities in Chiapas, Mexico |
title_full_unstemmed | Levels of Organochlorine Pesticides in Blood Plasma from Residents of Malaria-Endemic Communities in Chiapas, Mexico |
title_short | Levels of Organochlorine Pesticides in Blood Plasma from Residents of Malaria-Endemic Communities in Chiapas, Mexico |
title_sort | levels of organochlorine pesticides in blood plasma from residents of malaria-endemic communities in chiapas, mexico |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210989/ https://www.ncbi.nlm.nih.gov/pubmed/25310541 http://dx.doi.org/10.3390/ijerph111010444 |
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