PKCδ Promotes High Glucose Induced Renal Tubular Oxidative Damage via Regulating Activation and Translocation of p66Shc

Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease (ESRD). Renal tubular injury by overproduction of ROS in mitochondria plays a critical role in the pathogenesis of DKD. Evidences have shown that p66Shc was involved in renal tubular injury via mitochondrial-dependent ROS pr...

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Detalles Bibliográficos
Autores principales: Song, Panai, Yang, Shikun, Xiao, Li, Xu, Xiaoxuan, Tang, Chengyuan, Yang, Yuyan, Ma, Mingming, Zhu, Jiefu, Liu, Fuyou, Sun, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211144/
https://www.ncbi.nlm.nih.gov/pubmed/25371776
http://dx.doi.org/10.1155/2014/746531

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