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Systematic Analysis of Time-Series Gene Expression Data on Tumor Cell-Selective Apoptotic Responses to HDAC Inhibitors

SAHA (suberoylanilide hydroxamic acid or vorinostat) is the first nonselective histone deacetylase (HDAC) inhibitor approved by the US Food and Drug Administration (FDA). SAHA affects histone acetylation in chromatin and a variety of nonhistone substrates, thus influencing many cellular processes. I...

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Detalles Bibliográficos
Autores principales:	Qi, Yun-feng, Huang, Yan-xin, Dong, Yan, Zheng, Li-hua, Bao, Yong-li, Sun, Lu-guo, Wu, Yin, Yu, Chun-lei, Jiang, Hong-yu, Li, Yu-xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211306/ https://www.ncbi.nlm.nih.gov/pubmed/25371703 http://dx.doi.org/10.1155/2014/867289

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