Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation

In kidney transplantation, antibody-mediated allograft injury caused by donor HLA-specific antibodies (DSA) has recently been identified as one of the major causes of late graft loss. This paper gives a brief overview on the impact of DSA development on graft outcome in organ transplantation with a...

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Detalles Bibliográficos
Autores principales: Morath, Christian, Opelz, Gerhard, Zeier, Martin, Süsal, Caner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211317/
https://www.ncbi.nlm.nih.gov/pubmed/25374891
http://dx.doi.org/10.1155/2014/845040
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author Morath, Christian
Opelz, Gerhard
Zeier, Martin
Süsal, Caner
author_facet Morath, Christian
Opelz, Gerhard
Zeier, Martin
Süsal, Caner
author_sort Morath, Christian
collection PubMed
description In kidney transplantation, antibody-mediated allograft injury caused by donor HLA-specific antibodies (DSA) has recently been identified as one of the major causes of late graft loss. This paper gives a brief overview on the impact of DSA development on graft outcome in organ transplantation with a focus on risk factors for de novo alloantibody induction and recently published guidelines for monitoring of DSA during the posttransplant phase.
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spelling pubmed-42113172014-11-05 Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation Morath, Christian Opelz, Gerhard Zeier, Martin Süsal, Caner J Immunol Res Review Article In kidney transplantation, antibody-mediated allograft injury caused by donor HLA-specific antibodies (DSA) has recently been identified as one of the major causes of late graft loss. This paper gives a brief overview on the impact of DSA development on graft outcome in organ transplantation with a focus on risk factors for de novo alloantibody induction and recently published guidelines for monitoring of DSA during the posttransplant phase. Hindawi Publishing Corporation 2014 2014-10-13 /pmc/articles/PMC4211317/ /pubmed/25374891 http://dx.doi.org/10.1155/2014/845040 Text en Copyright © 2014 Christian Morath et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Morath, Christian
Opelz, Gerhard
Zeier, Martin
Süsal, Caner
Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation
title Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation
title_full Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation
title_fullStr Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation
title_full_unstemmed Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation
title_short Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation
title_sort clinical relevance of hla antibody monitoring after kidney transplantation
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211317/
https://www.ncbi.nlm.nih.gov/pubmed/25374891
http://dx.doi.org/10.1155/2014/845040
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