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Common themes in PrP signaling: the Src remains the same

The ability of the cellular prion protein (PrP(C)) to trigger intracellular signals appears central to neurodegeneration pathways, yet the physiological significance of such signals is rather puzzling. For instance, PrP(C) deregulation disrupts phenomena as diverse as synaptic transmission in mammal...

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Detalles Bibliográficos
Autores principales: Ochs, Katharina, Málaga-Trillo, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211543/
https://www.ncbi.nlm.nih.gov/pubmed/25364767
http://dx.doi.org/10.3389/fcell.2014.00063