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Classical and Alternative Activation and Metalloproteinase Expression Occurs in Foam Cell Macrophages in Male and Female ApoE Null Mice in the Absence of T and B Lymphocytes
Background: Rupture of advanced atherosclerotic plaques accounts for most life-threatening myocardial infarctions. Classical (M1) and alternative (M2) macrophage activation could promote atherosclerotic plaque progression and rupture by increasing production of proteases, including matrix metallopro...
Autores principales: | Hayes, Elaine Mo, Tsaousi, Aikaterini, Di Gregoli, Karina, Jenkinson, S. Rhiannon, Bond, Andrew R., Johnson, Jason L., Bevan, Laura, Thomas, Anita C., Newby, Andrew C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211548/ https://www.ncbi.nlm.nih.gov/pubmed/25389425 http://dx.doi.org/10.3389/fimmu.2014.00537 |
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