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Defining the conformation of human mincle that interacts with mycobacterial trehalose dimycolate

Trehalose dimycolate, an unusual glycolipid in the outer membrane of Mycobacterium tuberculosis, stimulates macrophages by binding to the macrophage receptor mincle. This stimulation plays an important role both in infection by mycobacteria and in the use of derivatives of mycobacteria as adjuvants...

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Detalles Bibliográficos
Autores principales:	Jégouzo, Sabine A F, Harding, Edward C, Acton, Oliver, Rex, Maximus J, Fadden, Andrew J, Taylor, Maureen E, Drickamer, Kurt
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211601/ https://www.ncbi.nlm.nih.gov/pubmed/25028392 http://dx.doi.org/10.1093/glycob/cwu072

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