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Physical Activity during Pregnancy and Offspring Neurodevelopment and IQ in the First 4 Years of Life

BACKGROUND: Maternal physical activity during pregnancy could alter offspring's IQ and neurodevelopment in childhood. METHODS: Children belonging to a birth cohort were followed at 3, 12, 24 and 48 months of age. Physical activity during pregnancy was assessed retrospectively at birth. Neurodev...

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Autores principales: Domingues, Marlos R., Matijasevich, Alicia, Barros, Aluísio J. D., Santos, Iná S., Horta, Bernardo L., Hallal, Pedro C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211660/
https://www.ncbi.nlm.nih.gov/pubmed/25350666
http://dx.doi.org/10.1371/journal.pone.0110050
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author Domingues, Marlos R.
Matijasevich, Alicia
Barros, Aluísio J. D.
Santos, Iná S.
Horta, Bernardo L.
Hallal, Pedro C.
author_facet Domingues, Marlos R.
Matijasevich, Alicia
Barros, Aluísio J. D.
Santos, Iná S.
Horta, Bernardo L.
Hallal, Pedro C.
author_sort Domingues, Marlos R.
collection PubMed
description BACKGROUND: Maternal physical activity during pregnancy could alter offspring's IQ and neurodevelopment in childhood. METHODS: Children belonging to a birth cohort were followed at 3, 12, 24 and 48 months of age. Physical activity during pregnancy was assessed retrospectively at birth. Neurodevelopment was evaluated by Battelle's Development Inventory (12, 24 and 48 months) and IQ by the Weschler's Intelligence Scale (48 months). Neurodevelopment was based on Battelles' (90th percentile) and also analyzed as a continuous outcome. IQ was analyzed as a continuous outcome. Potential confounders were: family income, mother's age, schooling, skin color, number of previous births and smoking; and newborns': preterm birth, sex and low birth weight. RESULTS: From birth to 48 months, sample size decreased from 4231 to 3792. Crude analysis showed that IQ at 48 months was slightly higher (5 points) among children from active women. The Battelle's score at 12 and 24 months was higher among offspring from active mothers. After controlling for confounders, physical activity during pregnancy was positively associated to the Battelle's Inventory at 12 months IQ, however, at 48 months no association was observed. CONCLUSION: Physical activity during pregnancy does not seem to impair children's neurodevelopment and children from active mothers presented better performance at 12 months.
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spelling pubmed-42116602014-11-05 Physical Activity during Pregnancy and Offspring Neurodevelopment and IQ in the First 4 Years of Life Domingues, Marlos R. Matijasevich, Alicia Barros, Aluísio J. D. Santos, Iná S. Horta, Bernardo L. Hallal, Pedro C. PLoS One Research Article BACKGROUND: Maternal physical activity during pregnancy could alter offspring's IQ and neurodevelopment in childhood. METHODS: Children belonging to a birth cohort were followed at 3, 12, 24 and 48 months of age. Physical activity during pregnancy was assessed retrospectively at birth. Neurodevelopment was evaluated by Battelle's Development Inventory (12, 24 and 48 months) and IQ by the Weschler's Intelligence Scale (48 months). Neurodevelopment was based on Battelles' (90th percentile) and also analyzed as a continuous outcome. IQ was analyzed as a continuous outcome. Potential confounders were: family income, mother's age, schooling, skin color, number of previous births and smoking; and newborns': preterm birth, sex and low birth weight. RESULTS: From birth to 48 months, sample size decreased from 4231 to 3792. Crude analysis showed that IQ at 48 months was slightly higher (5 points) among children from active women. The Battelle's score at 12 and 24 months was higher among offspring from active mothers. After controlling for confounders, physical activity during pregnancy was positively associated to the Battelle's Inventory at 12 months IQ, however, at 48 months no association was observed. CONCLUSION: Physical activity during pregnancy does not seem to impair children's neurodevelopment and children from active mothers presented better performance at 12 months. Public Library of Science 2014-10-28 /pmc/articles/PMC4211660/ /pubmed/25350666 http://dx.doi.org/10.1371/journal.pone.0110050 Text en © 2014 Domingues et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Domingues, Marlos R.
Matijasevich, Alicia
Barros, Aluísio J. D.
Santos, Iná S.
Horta, Bernardo L.
Hallal, Pedro C.
Physical Activity during Pregnancy and Offspring Neurodevelopment and IQ in the First 4 Years of Life
title Physical Activity during Pregnancy and Offspring Neurodevelopment and IQ in the First 4 Years of Life
title_full Physical Activity during Pregnancy and Offspring Neurodevelopment and IQ in the First 4 Years of Life
title_fullStr Physical Activity during Pregnancy and Offspring Neurodevelopment and IQ in the First 4 Years of Life
title_full_unstemmed Physical Activity during Pregnancy and Offspring Neurodevelopment and IQ in the First 4 Years of Life
title_short Physical Activity during Pregnancy and Offspring Neurodevelopment and IQ in the First 4 Years of Life
title_sort physical activity during pregnancy and offspring neurodevelopment and iq in the first 4 years of life
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211660/
https://www.ncbi.nlm.nih.gov/pubmed/25350666
http://dx.doi.org/10.1371/journal.pone.0110050
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