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The Causal Effect of Vitamin D Binding Protein (DBP) Levels on Calcemic and Cardiometabolic Diseases: A Mendelian Randomization Study
BACKGROUND: Observational studies have shown that vitamin D binding protein (DBP) levels, a key determinant of 25-hydroxy-vitamin D (25OHD) levels, and 25OHD levels themselves both associate with risk of disease. If 25OHD levels have a causal influence on disease, and DBP lies in this causal pathway...
Autores principales: | Leong, Aaron, Rehman, Waheed, Dastani, Zari, Greenwood, Celia, Timpson, Nicholas, Langsetmo, Lisa, Berger, Claudie, Fu, Lei, Wong, Betty Y. L., Malik, Suneil, Malik, Rainer, Hanley, David A., Cole, David E. C., Goltzman, David, Richards, J. Brent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211663/ https://www.ncbi.nlm.nih.gov/pubmed/25350643 http://dx.doi.org/10.1371/journal.pmed.1001751 |
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