β(2)-Adrenergic Receptor-Dependent Attenuation of Hypoxic Pulmonary Vasoconstriction Prevents Progression of Pulmonary Arterial Hypertension in Intermittent Hypoxic Rats

In sleep apnea syndrome (SAS), intermittent hypoxia (IH) induces repeated episodes of hypoxic pulmonary vasoconstriction (HPV) during sleep, which presumably contribute to pulmonary arterial hypertension (PAH). However, the prevalence of PAH was low and severity is mostly mild in SAS patients, and m...

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Detalles Bibliográficos
Autores principales: Nagai, Hisashi, Kuwahira, Ichiro, Schwenke, Daryl O., Tsuchimochi, Hirotsugu, Nara, Akina, Inagaki, Tadakatsu, Ogura, Sayoko, Fujii, Yutaka, Umetani, Keiji, Shimosawa, Tatsuo, Yoshida, Ken-ichi, Pearson, James T., Uemura, Koichi, Shirai, Mikiyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211686/
https://www.ncbi.nlm.nih.gov/pubmed/25350545
http://dx.doi.org/10.1371/journal.pone.0110693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211686/
https://www.ncbi.nlm.nih.gov/pubmed/25350545
http://dx.doi.org/10.1371/journal.pone.0110693

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