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Functional Characterization of Sticholysin I and W111C Mutant Reveals the Sequence of the Actinoporin’s Pore Assembly

The use of pore-forming toxins in the construction of immunotoxins against tumour cells is an alternative for cancer therapy. In this protein family one of the most potent toxins are the actinoporins, cytolysins from sea anemones. We work on the construction of tumour proteinase-activated immunotoxi...

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Detalles Bibliográficos
Autores principales:	Antonini, Valeria, Pérez-Barzaga, Victor, Bampi, Silvia, Pentón, David, Martínez, Diana, Serra, Mauro Dalla, Tejuca, Mayra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211696/ https://www.ncbi.nlm.nih.gov/pubmed/25350457 http://dx.doi.org/10.1371/journal.pone.0110824

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