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Engineering microorganisms based on molecular evolutionary analysis: a succinate production case study
Evolution has resulted in thousands of species possessing similar metabolic enzymes with identical functions that are, however, regulated by different mechanisms. It is thus difficult to select optimal gene to engineer novel or manipulated metabolic pathways. Here, we tested the ability of molecular...
Autores principales: | Ma, Xianghui, Zhang, Xinbo, Wang, Baiyun, Mao, Yufeng, Wang, Zhiwen, Chen, Tao, Zhao, Xueming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211721/ https://www.ncbi.nlm.nih.gov/pubmed/25469170 http://dx.doi.org/10.1111/eva.12186 |
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