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Bardoxolone methyl (CDDO-Me) as a therapeutic agent: an update on its pharmacokinetic and pharmacodynamic properties
Triterpenoids have been used for medicinal purposes in many Asian countries because of their anti-inflammatory, antioxidant, antiproliferative, anticancer, and anticarcinogenic properties. Bardoxolone methyl, the C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO) known as CDDO-...
Autores principales: | Wang, Yan-Yang, Yang, Yin-Xue, Zhe, Hong, He, Zhi-Xu, Zhou, Shu-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211867/ https://www.ncbi.nlm.nih.gov/pubmed/25364233 http://dx.doi.org/10.2147/DDDT.S68872 |
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