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Determination of factors controlling the particle size and entrapment efficiency of noscapine in PEG/PLA nanoparticles using artificial neural networks
In this study, di- and triblock copolymers based on polyethylene glycol and polylactide were synthesized by ring-opening polymerization and characterized by proton nuclear magnetic resonance and gel permeation chromatography. Nanoparticles containing noscapine were prepared from these biodegradable...
Autores principales: | Shalaby, Karim S, Soliman, Mahmoud E, Casettari, Luca, Bonacucina, Giulia, Cespi, Marco, Palmieri, Giovanni F, Sammour, Omaima A, El Shamy, Abdelhameed A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211908/ https://www.ncbi.nlm.nih.gov/pubmed/25364252 http://dx.doi.org/10.2147/IJN.S68737 |
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