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Allelic mapping bias in RNA-sequencing is not a major confounder in eQTL studies
BACKGROUND: RNA sequencing (RNA-seq) is the current gold-standard method to quantify gene expression for expression quantitative trait locus (eQTL) studies. However, a potential caveat in these studies is that RNA-seq reads carrying the non-reference allele of variant loci can have lower probability...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212091/ https://www.ncbi.nlm.nih.gov/pubmed/25239376 http://dx.doi.org/10.1186/s13059-014-0467-2 |