Leber’s hereditary optic neuropathy with late disease onset: clinical and molecular characteristics of 20 patients

BACKGROUND: Leber’s hereditary optic neuropathy (LHON) is a mitochondrial disease that typically causes bilateral blindness in young men. Here we describe the clinical and molecular characteristics of 20 patients with disease onset after the age of 50 years (late onset-LHON). METHODS: From a cohort...

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Detalles Bibliográficos
Autores principales: Dimitriadis, Konstantin, Leonhardt, Miriam, Yu-Wai-Man, Patrick, Kirkman, Matthew Anthony, Korsten, Alex, De Coo, Irenaeus F, Chinnery, Patrick Francis, Klopstock, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212093/
https://www.ncbi.nlm.nih.gov/pubmed/25338955
http://dx.doi.org/10.1186/s13023-014-0158-9

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