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Treatment crossovers in time-to-event non-inferiority randomised trials of radiotherapy in patients with breast cancer

BACKGROUND: In non-inferiority trials of radiotherapy in patients with early stage breast cancer, it is inevitable that some patients will cross over from the experimental arm to the standard arm prior to initiation of any treatment due to complexities in treatment planning or subject preference. Al...

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Detalles Bibliográficos
Autores principales: Parpia, Sameer, Julian, Jim A, Thabane, Lehana, Gu, Chushu, Whelan, Timothy J, Levine, Mark N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212183/
https://www.ncbi.nlm.nih.gov/pubmed/25344487
http://dx.doi.org/10.1136/bmjopen-2014-006531