The Presence of Telomere Fusion in Sporadic Colon Cancer Independently of Disease Stage, TP53/KRAS Mutation Status, Mean Telomere Length, and Telomerase Activity

Defects in telomere maintenance can result in telomere fusions that likely play a causative role in carcinogenesis by promoting genomic instability. However, this proposition remains to be fully understood in human colon carcinogenesis. In the present study, the temporal sequence of telomere dysfunc...

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Detalles Bibliográficos
Autores principales: Tanaka, Hiromi, Beam, Matthew J., Caruana, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212252/
https://www.ncbi.nlm.nih.gov/pubmed/25379018
http://dx.doi.org/10.1016/j.neo.2014.08.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212252/
https://www.ncbi.nlm.nih.gov/pubmed/25379018
http://dx.doi.org/10.1016/j.neo.2014.08.009

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