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CK2 Phosphorylates and Inhibits TAp73 Tumor Suppressor Function to Promote Expression of Cancer Stem Cell Genes and Phenotype in Head and Neck Cancer()()
Cancer stem cells (CSC) and genes have been linked to cancer development and therapeutic resistance, but the signaling mechanisms regulating CSC genes and phenotype are incompletely understood. CK2 has emerged as a key signal serine/threonine kinase that modulates diverse signal cascades regulating...
Autores principales: | Lu, Hai, Yan, Carol, Quan, Xin Xin, Yang, Xinping, Zhang, Jialing, Bian, Yansong, Chen, Zhong, Van Waes, Carter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212254/ https://www.ncbi.nlm.nih.gov/pubmed/25379016 http://dx.doi.org/10.1016/j.neo.2014.08.014 |
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