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Risk factors for wound infection in health care facilities in Buea, Cameroon: aerobic bacterial pathogens and antibiogram of isolates

INTRODUCTION: Wound infection is a significant clinical challenge in hospitals in developing countries where proper healthcare delivery is hampered by limited resources. This study investigated the antibiotic susceptibility pattern of bacteria causing wound infection and risk factors for infection a...

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Autores principales: Kihla, Akoachere Jane-Francis Tatah, Ngunde, Palle John, Evelyn, Mbianda Soupsop, Gerard, Nkwelang, Ndip, Roland Ndip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212436/
https://www.ncbi.nlm.nih.gov/pubmed/25360190
http://dx.doi.org/10.11604/pamj.2014.18.6.2304
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author Kihla, Akoachere Jane-Francis Tatah
Ngunde, Palle John
Evelyn, Mbianda Soupsop
Gerard, Nkwelang
Ndip, Roland Ndip
author_facet Kihla, Akoachere Jane-Francis Tatah
Ngunde, Palle John
Evelyn, Mbianda Soupsop
Gerard, Nkwelang
Ndip, Roland Ndip
author_sort Kihla, Akoachere Jane-Francis Tatah
collection PubMed
description INTRODUCTION: Wound infection is a significant clinical challenge in hospitals in developing countries where proper healthcare delivery is hampered by limited resources. This study investigated the antibiotic susceptibility pattern of bacteria causing wound infection and risk factors for infection among hospitalized patients in Buea, Cameroon, to generate findings which could drive reformation of policies on infection control. METHODS: Aerobic bacteria were isolated from 212 swabs collected from patients with clinically diagnosed infected wounds. Risk factors for wound infection were investigated. Antibiotic susceptibility of isolates was determined by disk diffusion technique. The Chi-square test was employed to determine significant differences in isolation and distribution of organisms in various specimens. Differences were considered significant at P < 0.05. RESULTS: Twelve bacteria species were isolated from 169 (79.7%) specimens. Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumoniae, the predominant isolates in all wound types exhibited a high preponderance of multidrug resistant strains. High rate of infection was attributed to lack of constant water supply and breakdown of sterilization equipment during the study period. Highest diversity of pathogens occurred in open wounds. There were no significant differences (P>0.05) in isolation of pathogens with respect to age, gender and wound type. Co-existing morbidity increased risk of wound infection. Isolates were susceptible to fluoroquinolones and resistant to oxacillin. CONCLUSION: Wound infection with resistant bacteria constitutes a significant cause of morbidity in the study area. Findings reiterate the need to strengthen infection control and drug dispensing policies, and greater collaboration between microbiologists and medical practioners to stem the spread of resistant bacteria.
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spelling pubmed-42124362014-10-30 Risk factors for wound infection in health care facilities in Buea, Cameroon: aerobic bacterial pathogens and antibiogram of isolates Kihla, Akoachere Jane-Francis Tatah Ngunde, Palle John Evelyn, Mbianda Soupsop Gerard, Nkwelang Ndip, Roland Ndip Pan Afr Med J Research INTRODUCTION: Wound infection is a significant clinical challenge in hospitals in developing countries where proper healthcare delivery is hampered by limited resources. This study investigated the antibiotic susceptibility pattern of bacteria causing wound infection and risk factors for infection among hospitalized patients in Buea, Cameroon, to generate findings which could drive reformation of policies on infection control. METHODS: Aerobic bacteria were isolated from 212 swabs collected from patients with clinically diagnosed infected wounds. Risk factors for wound infection were investigated. Antibiotic susceptibility of isolates was determined by disk diffusion technique. The Chi-square test was employed to determine significant differences in isolation and distribution of organisms in various specimens. Differences were considered significant at P < 0.05. RESULTS: Twelve bacteria species were isolated from 169 (79.7%) specimens. Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumoniae, the predominant isolates in all wound types exhibited a high preponderance of multidrug resistant strains. High rate of infection was attributed to lack of constant water supply and breakdown of sterilization equipment during the study period. Highest diversity of pathogens occurred in open wounds. There were no significant differences (P>0.05) in isolation of pathogens with respect to age, gender and wound type. Co-existing morbidity increased risk of wound infection. Isolates were susceptible to fluoroquinolones and resistant to oxacillin. CONCLUSION: Wound infection with resistant bacteria constitutes a significant cause of morbidity in the study area. Findings reiterate the need to strengthen infection control and drug dispensing policies, and greater collaboration between microbiologists and medical practioners to stem the spread of resistant bacteria. The African Field Epidemiology Network 2014-05-02 /pmc/articles/PMC4212436/ /pubmed/25360190 http://dx.doi.org/10.11604/pamj.2014.18.6.2304 Text en © Akoachere Jane-Francis Tatah Kihla et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Kihla, Akoachere Jane-Francis Tatah
Ngunde, Palle John
Evelyn, Mbianda Soupsop
Gerard, Nkwelang
Ndip, Roland Ndip
Risk factors for wound infection in health care facilities in Buea, Cameroon: aerobic bacterial pathogens and antibiogram of isolates
title Risk factors for wound infection in health care facilities in Buea, Cameroon: aerobic bacterial pathogens and antibiogram of isolates
title_full Risk factors for wound infection in health care facilities in Buea, Cameroon: aerobic bacterial pathogens and antibiogram of isolates
title_fullStr Risk factors for wound infection in health care facilities in Buea, Cameroon: aerobic bacterial pathogens and antibiogram of isolates
title_full_unstemmed Risk factors for wound infection in health care facilities in Buea, Cameroon: aerobic bacterial pathogens and antibiogram of isolates
title_short Risk factors for wound infection in health care facilities in Buea, Cameroon: aerobic bacterial pathogens and antibiogram of isolates
title_sort risk factors for wound infection in health care facilities in buea, cameroon: aerobic bacterial pathogens and antibiogram of isolates
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212436/
https://www.ncbi.nlm.nih.gov/pubmed/25360190
http://dx.doi.org/10.11604/pamj.2014.18.6.2304
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