Progressing small vessel pontine infarction includes different etiologies

BACKGROUND: The aim of this study was to investigate the clinical features of progressing stroke of pontine infarction as small vessel disease. METHODS: Enrolled 38 acute pontine infarctions were confirmed by magnetic resonance imaging and magnetic resonance angiography at the first and seventh days...

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Autores principales: Nakase, Taizen, Sasaki, Masahiro, Ikeda, Yasuko, Suzuki, Akifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212484/
https://www.ncbi.nlm.nih.gov/pubmed/25356386
http://dx.doi.org/10.1002/acn3.25
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author Nakase, Taizen
Sasaki, Masahiro
Ikeda, Yasuko
Suzuki, Akifumi
author_facet Nakase, Taizen
Sasaki, Masahiro
Ikeda, Yasuko
Suzuki, Akifumi
author_sort Nakase, Taizen
collection PubMed
description BACKGROUND: The aim of this study was to investigate the clinical features of progressing stroke of pontine infarction as small vessel disease. METHODS: Enrolled 38 acute pontine infarctions were confirmed by magnetic resonance imaging and magnetic resonance angiography at the first and seventh days. Ten patients (26.3%) presented progression (NIH Stroke Scale ≥2 increase within 72 h). RESULTS: Progressing patients showed no relation to the size and the distribution of lesion. Expansion of ischemic lesion showed correlation with basilar artery atherosclerosis. Stable lesion related to delayed worsening. CONCLUSION: These findings suggest that progressing stroke may be caused by not only the worsening of blood flow of ischemic lesion but also delayed neuronal death.
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spelling pubmed-42124842014-10-29 Progressing small vessel pontine infarction includes different etiologies Nakase, Taizen Sasaki, Masahiro Ikeda, Yasuko Suzuki, Akifumi Ann Clin Transl Neurol Research Papers BACKGROUND: The aim of this study was to investigate the clinical features of progressing stroke of pontine infarction as small vessel disease. METHODS: Enrolled 38 acute pontine infarctions were confirmed by magnetic resonance imaging and magnetic resonance angiography at the first and seventh days. Ten patients (26.3%) presented progression (NIH Stroke Scale ≥2 increase within 72 h). RESULTS: Progressing patients showed no relation to the size and the distribution of lesion. Expansion of ischemic lesion showed correlation with basilar artery atherosclerosis. Stable lesion related to delayed worsening. CONCLUSION: These findings suggest that progressing stroke may be caused by not only the worsening of blood flow of ischemic lesion but also delayed neuronal death. BlackWell Publishing Ltd 2014-02 2013-12-30 /pmc/articles/PMC4212484/ /pubmed/25356386 http://dx.doi.org/10.1002/acn3.25 Text en © 2013 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Research Papers
Nakase, Taizen
Sasaki, Masahiro
Ikeda, Yasuko
Suzuki, Akifumi
Progressing small vessel pontine infarction includes different etiologies
title Progressing small vessel pontine infarction includes different etiologies
title_full Progressing small vessel pontine infarction includes different etiologies
title_fullStr Progressing small vessel pontine infarction includes different etiologies
title_full_unstemmed Progressing small vessel pontine infarction includes different etiologies
title_short Progressing small vessel pontine infarction includes different etiologies
title_sort progressing small vessel pontine infarction includes different etiologies
topic Research Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212484/
https://www.ncbi.nlm.nih.gov/pubmed/25356386
http://dx.doi.org/10.1002/acn3.25
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AT ikedayasuko progressingsmallvesselpontineinfarctionincludesdifferentetiologies
AT suzukiakifumi progressingsmallvesselpontineinfarctionincludesdifferentetiologies

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