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Development and Characterization of Novel Site Specific Hollow Floating Microspheres Bearing 5-Fu for Stomach Targeting

Multiple-unit-type oral floating hollow microspheres of 5-fluorouracil (5-Fu) were developed using modified solvent evaporation technique to prolong gastric residence time, to target stomach cancer, and to increase drug bioavailability. The prepared microspheres were characterized for micromeritic p...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Peeyush, Chaurasia, Deepti, Singh, Ranjit, Swarup, Anoop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212548/
https://www.ncbi.nlm.nih.gov/pubmed/25383377
http://dx.doi.org/10.1155/2014/705259