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Serum α-hydroxybutyrate (α-HB) predicts elevated 1 h glucose levels and early-phase β-cell dysfunction during OGTT
OBJECTIVE: Serum α-hydroxybutyrate (α-HB) is elevated in insulin resistance and diabetes. We tested the hypothesis that the α-HB level predicts abnormal 1 h glucose levels and β-cell dysfunction inferred from plasma insulin kinetics during a 75 g oral glucose tolerance test (OGTT). RESEARCH DESIGN A...
Autores principales: | Varvel, Stephen A, Pottala, James V, Thiselton, Dawn L, Caffrey, Rebecca, Dall, Tara, Sasinowski, Maciek, McConnell, Joseph P, Warnick, G Russell, Voros, Szilard, Graham, Timothy E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212560/ https://www.ncbi.nlm.nih.gov/pubmed/25452875 http://dx.doi.org/10.1136/bmjdrc-2014-000038 |
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