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Layer-by-Layer Assembled Antisense DNA Microsponge Particles for Efficient Delivery of Cancer Therapeutics
[Image: see text] Antisense oligonucleotides can be employed as a potential approach to effectively treat cancer. However, the inherent instability and inefficient systemic delivery methods for antisense therapeutics remain major challenges to their clinical application. Here, we present a polymeriz...
Autores principales: | Roh, Young Hoon, Lee, Jong Bum, Shopsowitz, Kevin E., Dreaden, Erik C., Morton, Stephen W., Poon, Zhiyong, Hong, Jinkee, Yamin, Inbar, Bonner, Daniel K., Hammond, Paula T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212789/ https://www.ncbi.nlm.nih.gov/pubmed/25198246 http://dx.doi.org/10.1021/nn502596b |
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