Engineering Acetyl Coenzyme A Supply: Functional Expression of a Bacterial Pyruvate Dehydrogenase Complex in the Cytosol of Saccharomyces cerevisiae

The energetic (ATP) cost of biochemical pathways critically determines the maximum yield of metabolites of vital or commercial relevance. Cytosolic acetyl coenzyme A (acetyl-CoA) is a key precursor for biosynthesis in eukaryotes and for many industrially relevant product pathways that have been intr...

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Detalles Bibliográficos
Autores principales: Kozak, Barbara U., van Rossum, Harmen M., Luttik, Marijke A. H., Akeroyd, Michiel, Benjamin, Kirsten R., Wu, Liang, de Vries, Simon, Daran, Jean-Marc, Pronk, Jack T., van Maris, Antonius J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212835/
https://www.ncbi.nlm.nih.gov/pubmed/25336454
http://dx.doi.org/10.1128/mBio.01696-14

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