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CD8 T Cells in Innate Immune Responses: Using STAT4-Dependent but Antigen-Independent Pathways to Gamma Interferon during Viral Infection

The cytokine gamma interferon (IFN-γ), with antimicrobial and immunoregulatory functions, can be produced by T cells following stimulation through their T cell receptors (TCRs) for antigen. The innate cytokines type 1 IFNs and interleukin-12 (IL-12) can also stimulate IFN-γ production by natural kil...

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Detalles Bibliográficos
Autores principales: Suarez-Ramirez, Jenny E., Tarrio, Margarite L., Kim, Kwangsin, Demers, Delia A., Biron, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212840/
https://www.ncbi.nlm.nih.gov/pubmed/25336459
http://dx.doi.org/10.1128/mBio.01978-14