Cargando…

The serodominant secreted effector protein of Salmonella, SseB, is a strong CD4 antigen containing an immunodominant epitope presented by diverse HLA class II alleles

Detailed characterization of the protective T-cell response in salmonellosis is a pressing unmet need in light of the global burden of human Salmonella infections and the likely contribution of CD4 T cells to immunity against this intracellular infection. In previous studies screening patient sera a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Reynolds, Catherine J, Jones, Claire, Blohmke, Christoph J, Darton, Thomas C, Goudet, Amelie, Sergeant, Ruhena, Maillere, Bernard, Pollard, Andrew J, Altmann, Daniel M, Boyton, Rosemary J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Science Inc 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212957/ https://www.ncbi.nlm.nih.gov/pubmed/24891088 http://dx.doi.org/10.1111/imm.12327

Ejemplares similares

Immunogenicity and protective efficacy of nanoparticle formulations of L-SseB against Salmonella infection
por: Das, Sayan, et al.
Publicado: (2023)

Salmonella Enteritidis Subunit Vaccine Candidate Based on SseB Protein Co-Delivered with Simvastatin as Adjuvant
por: Kang, Xilong, et al.
Publicado: (2022)

KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells
por: Sim, Malcolm J. W., et al.
Publicado: (2015)

T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses
por: Reynolds, C. J., et al.
Publicado: (2018)

BIITE: A Tool to Determine HLA Class II Epitopes from T Cell ELISpot Data
por: Boelen, Lies, et al.
Publicado: (2016)

Serodominant SARS-CoV-2 Nucleocapsid Peptides Map to Unstructured Protein Regions
por: Vandervaart, Jacob P., et al.
Publicado: (2023)

MS in South Asians in England: early disease onset and novel pattern of myelin autoimmunity
por: Nicholas, Richard S, et al.
Publicado: (2015)

Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C
por: Sim, Malcolm J. W., et al.
Publicado: (2019)

Structural basis for the glycosyltransferase activity of the Salmonella effector SseK3
por: Esposito, Diego, et al.
Publicado: (2018)

The Salmonella Effector SseK3 Targets Small Rab GTPases
por: Gan, Jiyao, et al.
Publicado: (2020)

Increased HLA-E expression in white matter lesions in multiple sclerosis
por: Durrenberger, Pascal F, et al.
Publicado: (2012)

Salmonella Effectors SseF and SseG Interact with Mammalian Protein ACBD3 (GCP60) To Anchor Salmonella-Containing Vacuoles at the Golgi Network
por: Yu, Xiu-Jun, et al.
Publicado: (2016)

Impact of HLA Polymorphism on the Immune Response to Bacillus Anthracis Protective Antigen in Vaccination versus Natural Infection
por: Ascough, Stephanie, et al.
Publicado: (2022)

Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope
por: Cole, David K., et al.
Publicado: (2017)

Multiplexed gene expression analysis of HLA class II-associated podoconiosis implicates chronic immune activation in its pathogenesis
por: Alcantara, Diana R, et al.
Publicado: (2020)

Functional Dissection of SseF, a Membrane-Integral Effector Protein of Intracellular Salmonella enterica
por: Müller, Petra, et al.
Publicado: (2012)

Tubulin Folding Cofactor TBCB is a Target of the Salmonella Effector Protein SseK1
por: Araujo-Garrido, Juan Luis, et al.
Publicado: (2020)

SseK1 and SseK3 Type III Secretion System Effectors Inhibit NF-κB Signaling and Necroptotic Cell Death in Salmonella-Infected Macrophages
por: Günster, Regina A., et al.
Publicado: (2017)

Risk of SARS-CoV-2 reinfection after natural infection
por: Boyton, Rosemary J, et al.
Publicado: (2021)

Waning immunity to SARS-CoV-2: implications for vaccine booster strategies
por: Altmann, Daniel M, et al.
Publicado: (2021)

Vaccine efficacy and immune interference: co-administering COVID-19 and influenza vaccines
por: Altmann, Daniel M, et al.
Publicado: (2022)

The immunology of asymptomatic SARS-CoV-2 infection: what are the key questions?
por: Boyton, Rosemary J., et al.
Publicado: (2021)

SARS-Cov-2 immune waning and reinfection in care-home settings
por: Altmann, Daniel M, et al.
Publicado: (2021)

Redirected vaccine imprinting by co-administration of COVID-19 and influenza vaccines
por: Boyton, Rosemary J., et al.
Publicado: (2023)

Imprinted hybrid immunity against XBB reinfection
por: Boyton, Rosemary J, et al.
Publicado: (2023)

Salmonella Phage ST64B Encodes a Member of the SseK/NleB Effector Family
por: Brown, Nat F., et al.
Publicado: (2011)

Anthrax Lethal Factor as an Immune Target in Humans and Transgenic Mice and the Impact of HLA Polymorphism on CD4(+) T Cell Immunity
por: Ascough, Stephanie, et al.
Publicado: (2014)

Infection with Burkholderia pseudomallei – immune correlates of survival in acute melioidosis
por: Dunachie, Susanna J., et al.
Publicado: (2017)

Immune Control of Burkholderia pseudomallei––Common, High-Frequency T-Cell Responses to a Broad Repertoire of Immunoprevalent Epitopes
por: Nithichanon, Arnone, et al.
Publicado: (2018)

Canonical and Cross-reactive Binding of NK Cell Inhibitory Receptors to HLA-C Allotypes Is Dictated by Peptides Bound to HLA-C
por: Sim, Malcolm J. W., et al.
Publicado: (2017)

CD4+ T Cells Targeting Dominant and Cryptic Epitopes from Bacillus anthracis Lethal Factor
por: Ascough, Stephanie, et al.
Publicado: (2016)

Immunodominant Tuberculosis CD8 Antigens Preferentially Restricted by HLA-B
por: Lewinsohn, Deborah A, et al.
Publicado: (2007)

The Salmonella effector SseJ disrupts microtubule dynamics when ectopically expressed in normal rat kidney cells
por: Raines, Sally A., et al.
Publicado: (2017)

SARS-CoV-2 variants: Subversion of antibody response and predicted impact on T cell recognition
por: Altmann, Daniel M., et al.
Publicado: (2021)

Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality
por: Mkhwanazi, Nompumelelo, et al.
Publicado: (2010)

A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape
por: Kløverpris, Henrik N, et al.
Publicado: (2015)

Patterns of Immunodominance in HIV-1–specific Cytotoxic T Lymphocyte Responses in Two Human Histocompatibility Leukocyte Antigens (HLA)-identical Siblings with HLA-A*0201 Are Influenced by Epitope Mutation
por: Goulder, P.J.R., et al.
Publicado: (1997)

Blood culture-PCR to optimise typhoid fever diagnosis after controlled human infection identifies frequent asymptomatic cases and evidence of primary bacteraemia
por: Darton, Thomas C., et al.
Publicado: (2017)

What policy makers need to know about COVID-19 protective immunity
por: Altmann, Daniel M, et al.
Publicado: (2020)

The Salmonella SPI2 Effector SseI Mediates Long-Term Systemic Infection by Modulating Host Cell Migration
por: McLaughlin, Laura M., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_n6hvdl4k7cmjvjpdufkn0gp60t