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Genomic Imprinting Variations in the Mouse Type 3 Deiodinase Gene Between Tissues and Brain Regions

The Dio3 gene, which encodes for the type 3 deiodinase (D3), controls thyroid hormone (TH) availability. The lack of D3 in mice results in tissue overexposure to TH and a broad neuroendocrine phenotype. Dio3 is an imprinted gene, preferentially expressed from the paternally inherited allele in the m...

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Detalles Bibliográficos
Autores principales:	Martinez, M. Elena, Charalambous, Marika, Saferali, Aabida, Fiering, Steven, Naumova, Anna K., St Germain, Donald, Ferguson-Smith, Anne C., Hernandez, Arturo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213365/ https://www.ncbi.nlm.nih.gov/pubmed/25232934 http://dx.doi.org/10.1210/me.2014-1210

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