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The effect of the severity of liver cirrhosis on the level of lipids and lipoproteins
The effect of severity of liver cirrhosis, an alcoholic and non-alcoholic genesis, on the results of serum lipids and lipoproteins was evaluated. Serum cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL-Ch), and low-density lipoprotein cholesterol (LDL-Ch) were measured in the ser...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Milan
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213382/ https://www.ncbi.nlm.nih.gov/pubmed/24122348 http://dx.doi.org/10.1007/s10238-013-0262-5 |
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author | Chrostek, Lech Supronowicz, Lukasz Panasiuk, Anatol Cylwik, Bogdan Gruszewska, Ewa Flisiak, Robert |
author_facet | Chrostek, Lech Supronowicz, Lukasz Panasiuk, Anatol Cylwik, Bogdan Gruszewska, Ewa Flisiak, Robert |
author_sort | Chrostek, Lech |
collection | PubMed |
description | The effect of severity of liver cirrhosis, an alcoholic and non-alcoholic genesis, on the results of serum lipids and lipoproteins was evaluated. Serum cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL-Ch), and low-density lipoprotein cholesterol (LDL-Ch) were measured in the sera of 59 patients suffering from alcoholic cirrhosis and 34 patients with non-alcoholic cirrhosis. The level of serum triglycerides depends on the severity of liver damage in alcoholic liver cirrhosis, being the highest in Child-Pugh score B. The severity of liver damage significantly affects the HDL-Ch and LDL-Ch levels in cirrhosis of non-alcoholic origin, reaching the highest value for LDL-Ch and the lowest for HDL-Ch in score C. It should not be generalized that the levels of lipids and lipoproteins in liver cirrhosis progressively diminished with the deterioration of liver function. The serum HDL-Ch and LDL-Ch may be considered as markers of severity of liver damage in non-alcoholic cirrhosis, but the triglycerides only in disease of alcoholic origin. |
format | Online Article Text |
id | pubmed-4213382 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Springer Milan |
record_format | MEDLINE/PubMed |
spelling | pubmed-42133822014-11-03 The effect of the severity of liver cirrhosis on the level of lipids and lipoproteins Chrostek, Lech Supronowicz, Lukasz Panasiuk, Anatol Cylwik, Bogdan Gruszewska, Ewa Flisiak, Robert Clin Exp Med Original Article The effect of severity of liver cirrhosis, an alcoholic and non-alcoholic genesis, on the results of serum lipids and lipoproteins was evaluated. Serum cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL-Ch), and low-density lipoprotein cholesterol (LDL-Ch) were measured in the sera of 59 patients suffering from alcoholic cirrhosis and 34 patients with non-alcoholic cirrhosis. The level of serum triglycerides depends on the severity of liver damage in alcoholic liver cirrhosis, being the highest in Child-Pugh score B. The severity of liver damage significantly affects the HDL-Ch and LDL-Ch levels in cirrhosis of non-alcoholic origin, reaching the highest value for LDL-Ch and the lowest for HDL-Ch in score C. It should not be generalized that the levels of lipids and lipoproteins in liver cirrhosis progressively diminished with the deterioration of liver function. The serum HDL-Ch and LDL-Ch may be considered as markers of severity of liver damage in non-alcoholic cirrhosis, but the triglycerides only in disease of alcoholic origin. Springer Milan 2013-10-12 2014 /pmc/articles/PMC4213382/ /pubmed/24122348 http://dx.doi.org/10.1007/s10238-013-0262-5 Text en © The Author(s) 2013 https://creativecommons.org/licenses/by/2.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Original Article Chrostek, Lech Supronowicz, Lukasz Panasiuk, Anatol Cylwik, Bogdan Gruszewska, Ewa Flisiak, Robert The effect of the severity of liver cirrhosis on the level of lipids and lipoproteins |
title | The effect of the severity of liver cirrhosis on the level of lipids and lipoproteins |
title_full | The effect of the severity of liver cirrhosis on the level of lipids and lipoproteins |
title_fullStr | The effect of the severity of liver cirrhosis on the level of lipids and lipoproteins |
title_full_unstemmed | The effect of the severity of liver cirrhosis on the level of lipids and lipoproteins |
title_short | The effect of the severity of liver cirrhosis on the level of lipids and lipoproteins |
title_sort | effect of the severity of liver cirrhosis on the level of lipids and lipoproteins |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213382/ https://www.ncbi.nlm.nih.gov/pubmed/24122348 http://dx.doi.org/10.1007/s10238-013-0262-5 |
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