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Understanding disease mechanisms with models of signaling pathway activities

BACKGROUND: Understanding the aspects of the cell functionality that account for disease or drug action mechanisms is one of the main challenges in the analysis of genomic data and is on the basis of the future implementation of precision medicine. RESULTS: Here we propose a simple probabilistic mod...

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Detalles Bibliográficos
Autores principales:	Sebastian-Leon, Patricia, Vidal, Enrique, Minguez, Pablo, Conesa, Ana, Tarazona, Sonia, Amadoz, Alicia, Armero, Carmen, Salavert, Francisco, Vidal-Puig, Antonio, Montaner, David, Dopazo, Joaquín
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213475/ https://www.ncbi.nlm.nih.gov/pubmed/25344409 http://dx.doi.org/10.1186/s12918-014-0121-3

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