Pim-1 kinase is a target of miR-486-5p and eukaryotic translation initiation factor 4E, and plays a critical role in lung cancer

BACKGROUND: Pim-1 kinase is a proto-oncogene and its dysregulation contributes to tumorigenesis and progression of a variety of malignancies. Pim-1 was suggested as a therapeutic target of cancers. The functional relevance of Pim-1 and the mechanism underlying its dysregulation in lung tumorigenesis...

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Detalles Bibliográficos
Autores principales: Pang, Wenshuai, Tian, Xin, Bai, Fan, Han, Ruiyu, Wang, Juan, Shen, Haitao, Zhang, Xianghong, Liu, Yueping, Yan, Xia, Jiang, Feng, Xing, Lingxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213487/
https://www.ncbi.nlm.nih.gov/pubmed/25342548
http://dx.doi.org/10.1186/1476-4598-13-240

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