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Functional consequences of somatic mutations in cancer using protein pocket-based prioritization approach
BACKGROUND: Recently, a number of large-scale cancer genome sequencing projects have generated a large volume of somatic mutations; however, identifying the functional consequences and roles of somatic mutations in tumorigenesis remains a major challenge. Researchers have identified that protein poc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213513/ https://www.ncbi.nlm.nih.gov/pubmed/25360158 http://dx.doi.org/10.1186/s13073-014-0081-7 |