Defective IL-17- and IL-22-dependent mucosal host response to Candida albicans determines susceptibility to oral candidiasis in mice expressing the HIV-1 transgene

BACKGROUND: The tissue-signaling cytokines IL-17 and IL-22 are critical to host defense against oral Candida albicans infection, by their induction of oral antimicrobial peptide expression and recruitment of neutrophils. Mucosal Th17 cells which produce these cytokines are preferentially depleted in...

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Detalles Bibliográficos
Autores principales: Goupil, Mathieu, Cousineau-Côté, Vincent, Aumont, Francine, Sénéchal, Serge, Gaboury, Louis, Hanna, Zaher, Jolicoeur, Paul, de Repentigny, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213580/
https://www.ncbi.nlm.nih.gov/pubmed/25344377
http://dx.doi.org/10.1186/s12865-014-0049-9

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