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Extracellular ATP does not induce P2X7 receptor-dependent responses in cultured renal- and liver-derived swine macrophages

The P2X7 receptor (P2X7R) is an ATP-gated cation channel that is abundantly expressed in monocytes/macrophages. P2X7R activation by ATP results in various cellular responses including Ca(2+) influx, membrane pore formation, and cytokine secretion. Since P2X7R has low affinity for ATP, high concentra...

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Detalles Bibliográficos
Autores principales:	Takenouchi, Takato, Suzuki, Shunichi, Shinkai, Hiroki, Tsukimoto, Mitsutoshi, Sato, Mitsuru, Uenishi, Hirohide, Kitani, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213840/ https://www.ncbi.nlm.nih.gov/pubmed/25379376 http://dx.doi.org/10.1016/j.rinim.2014.07.002

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