Systematic review of the concept of Yakrutotpatti (embryology of liver)

Ayurveda has its own view to understand the development of human body and its various organs. As the quotations are in a concise manner, it is essential to amalgamate the basics stated by various Acharyas with comprehensive explanation of modern science. The liver is a vital organ for metabolism. Acharyas have opined about the genesis of Yakrut (liver) from Rakta Dhatu (blood tissue). Parallel opinion in conventional anatomy states that abundant quantity of blood is responsible for the formation of sinusoids of liver. This huge quantity of blood comes from broken viteline and umbilical veins in the septum transversum. On the other hand, the raw material for the formation of blood cells and liver (septum transversum) is the same, being mesenchymal cells from the mesoderm. The present review was conducted to discover the similarities about the genesis of liver in the opinions of ancient and conventional medical science. This may be useful for utilizing the ancient medical science in a new perspective. Therefore, it is attempted to correlate the genesis of liver in Ayurveda with modern science.