Preparation and pharmaceutical evaluation of nicotinamide stick for eradication of Staphylococcus epidermidis

BACKGROUND: Staphylococcus epidermidis is a part of the skin's normal flora that can cause acne. This study was designed to evaluate the efficacy of nicotinamide as a stick in eradication of staphylococcus. MATERIALS AND METHODS: For evaluating of Anti-microbial effect on S. epidermidis used we...

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Detalles Bibliográficos
Autores principales: Shahtalebi, Mohammad Ali, Bahrinajafi, Rahim, Nahavandi, Sima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214026/
https://www.ncbi.nlm.nih.gov/pubmed/25364367
Descripción
Sumario:BACKGROUND: Staphylococcus epidermidis is a part of the skin's normal flora that can cause acne. This study was designed to evaluate the efficacy of nicotinamide as a stick in eradication of staphylococcus. MATERIALS AND METHODS: For evaluating of Anti-microbial effect on S. epidermidis used well plate method. We chose five plates for nicotinamide and five for mupirocin. The zones of inhibition were measured and compared. RESULTS: The results showed nicotinamide stick had anti-microbial effects, but in comparison to mupirocin it was significantly less (P = 0.003). CONCLUSION: Nicotinamide stick was made and evaluated. This study showed that nicotinamide had anti-microbial effect on staphylococcus.

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