Epigenetic advances in clinical neuroscience
Epigenetics, broadly defined as the regulation of gene expression without alteration of the genome, has become a field of tremendous interest in neuroscience, neurology, and psychiatry. This research has rapidly changed the way researchers think about brain function. Exciting epigenetic discoveries...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Les Laboratoires Servier
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214171/ https://www.ncbi.nlm.nih.gov/pubmed/25364279 |
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author | Abel, Ted Poplawski, Shane |
author_facet | Abel, Ted Poplawski, Shane |
author_sort | Abel, Ted |
collection | PubMed |
description | Epigenetics, broadly defined as the regulation of gene expression without alteration of the genome, has become a field of tremendous interest in neuroscience, neurology, and psychiatry. This research has rapidly changed the way researchers think about brain function. Exciting epigenetic discoveries have been found in addiction, early life stress, neurodegeneration, post-traumatic stress disorder, and depression. As researchers more precisely define the epigenetic landscape that regulates disease progression in each of these cases, therapeutics can be designed to specifically target the molecules that mediate these epigenetic processes. Further, epigenetics may lead, to the identification of novel biomarkers for diagnosis and for the monitoring of treatment. Epigenetic profiling is likely to become a routine tool for the diagnosis of neurological and psychiatric disorders in the near future. |
format | Online Article Text |
id | pubmed-4214171 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Les Laboratoires Servier |
record_format | MEDLINE/PubMed |
spelling | pubmed-42141712014-10-31 Epigenetic advances in clinical neuroscience Abel, Ted Poplawski, Shane Dialogues Clin Neurosci Guest Editorial Epigenetics, broadly defined as the regulation of gene expression without alteration of the genome, has become a field of tremendous interest in neuroscience, neurology, and psychiatry. This research has rapidly changed the way researchers think about brain function. Exciting epigenetic discoveries have been found in addiction, early life stress, neurodegeneration, post-traumatic stress disorder, and depression. As researchers more precisely define the epigenetic landscape that regulates disease progression in each of these cases, therapeutics can be designed to specifically target the molecules that mediate these epigenetic processes. Further, epigenetics may lead, to the identification of novel biomarkers for diagnosis and for the monitoring of treatment. Epigenetic profiling is likely to become a routine tool for the diagnosis of neurological and psychiatric disorders in the near future. Les Laboratoires Servier 2014-09 /pmc/articles/PMC4214171/ /pubmed/25364279 Text en Copyright: © 2014 Institut la Conférence Hippocrate - Servier Research Group http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Guest Editorial Abel, Ted Poplawski, Shane Epigenetic advances in clinical neuroscience |
title | Epigenetic advances in clinical neuroscience |
title_full | Epigenetic advances in clinical neuroscience |
title_fullStr | Epigenetic advances in clinical neuroscience |
title_full_unstemmed | Epigenetic advances in clinical neuroscience |
title_short | Epigenetic advances in clinical neuroscience |
title_sort | epigenetic advances in clinical neuroscience |
topic | Guest Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214171/ https://www.ncbi.nlm.nih.gov/pubmed/25364279 |
work_keys_str_mv | AT abelted epigeneticadvancesinclinicalneuroscience AT poplawskishane epigeneticadvancesinclinicalneuroscience |