Epigenetic advances in clinical neuroscience

Epigenetics, broadly defined as the regulation of gene expression without alteration of the genome, has become a field of tremendous interest in neuroscience, neurology, and psychiatry. This research has rapidly changed the way researchers think about brain function. Exciting epigenetic discoveries...

Descripción completa

Detalles Bibliográficos
Autores principales: Abel, Ted, Poplawski, Shane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Les Laboratoires Servier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214171/
https://www.ncbi.nlm.nih.gov/pubmed/25364279
_version_ 1782341918200430592
author Abel, Ted
Poplawski, Shane
author_facet Abel, Ted
Poplawski, Shane
author_sort Abel, Ted
collection PubMed
description Epigenetics, broadly defined as the regulation of gene expression without alteration of the genome, has become a field of tremendous interest in neuroscience, neurology, and psychiatry. This research has rapidly changed the way researchers think about brain function. Exciting epigenetic discoveries have been found in addiction, early life stress, neurodegeneration, post-traumatic stress disorder, and depression. As researchers more precisely define the epigenetic landscape that regulates disease progression in each of these cases, therapeutics can be designed to specifically target the molecules that mediate these epigenetic processes. Further, epigenetics may lead, to the identification of novel biomarkers for diagnosis and for the monitoring of treatment. Epigenetic profiling is likely to become a routine tool for the diagnosis of neurological and psychiatric disorders in the near future.
format Online
Article
Text
id pubmed-4214171
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Les Laboratoires Servier
record_format MEDLINE/PubMed
spelling pubmed-42141712014-10-31 Epigenetic advances in clinical neuroscience Abel, Ted Poplawski, Shane Dialogues Clin Neurosci Guest Editorial Epigenetics, broadly defined as the regulation of gene expression without alteration of the genome, has become a field of tremendous interest in neuroscience, neurology, and psychiatry. This research has rapidly changed the way researchers think about brain function. Exciting epigenetic discoveries have been found in addiction, early life stress, neurodegeneration, post-traumatic stress disorder, and depression. As researchers more precisely define the epigenetic landscape that regulates disease progression in each of these cases, therapeutics can be designed to specifically target the molecules that mediate these epigenetic processes. Further, epigenetics may lead, to the identification of novel biomarkers for diagnosis and for the monitoring of treatment. Epigenetic profiling is likely to become a routine tool for the diagnosis of neurological and psychiatric disorders in the near future. Les Laboratoires Servier 2014-09 /pmc/articles/PMC4214171/ /pubmed/25364279 Text en Copyright: © 2014 Institut la Conférence Hippocrate - Servier Research Group http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Guest Editorial
Abel, Ted
Poplawski, Shane
Epigenetic advances in clinical neuroscience
title Epigenetic advances in clinical neuroscience
title_full Epigenetic advances in clinical neuroscience
title_fullStr Epigenetic advances in clinical neuroscience
title_full_unstemmed Epigenetic advances in clinical neuroscience
title_short Epigenetic advances in clinical neuroscience
title_sort epigenetic advances in clinical neuroscience
topic Guest Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214171/
https://www.ncbi.nlm.nih.gov/pubmed/25364279
work_keys_str_mv AT abelted epigeneticadvancesinclinicalneuroscience
AT poplawskishane epigeneticadvancesinclinicalneuroscience