Cargando…

Garlic-derived compound S-allylmercaptocysteine inhibits cell growth and induces apoptosis via the JNK and p38 pathways in human colorectal carcinoma cells

S-allylmercaptocysteine (SAMC) is an active compound that is derived from garlic and has been demonstrated to possess antitumor properties in vitro. The present study aimed to investigate the effect of SAMC and determine the underlying mechanism of this effect on human colorectal carcinoma cells. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	ZHANG, YAN, LI, HONG-YAN, ZHANG, ZHI-HUA, BIAN, HONG-LEI, LIN, GUI
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214450/ https://www.ncbi.nlm.nih.gov/pubmed/25364433 http://dx.doi.org/10.3892/ol.2014.2579

Ejemplares similares

Garlic-derived compound S-allylmercaptocysteine inhibits hepatocarcinogenesis through targeting LRP6/Wnt pathway
por: Xiao, Jia, et al.
Publicado: (2018)

The Effect of Garlic Derivatives (S-Allylmercaptocysteine, Diallyl Disulfide, and S-Allylcysteine) on Gentamicin Induced Ototoxicity: An Experimental Study
por: Uzun, Lokman, et al.
Publicado: (2016)

Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy
por: Xiao, Jia, et al.
Publicado: (2013)

Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model
por: Xiao, Jia, et al.
Publicado: (2012)

S-Allylmercaptocysteine Attenuates Cisplatin-Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation
por: Zhu, Xiaosong, et al.
Publicado: (2017)

S-Allylmercaptocysteine improves alcoholic liver disease partly through a direct modulation of insulin receptor signaling
por: Luo, Pingping, et al.
Publicado: (2021)

Protective Effects of Garlic-Derived S-Allylmercaptocysteine on IL-1β-Stimulated Chondrocytes by Regulation of MMPs/TIMP-1 Ratio and Type II Collagen Expression via Suppression of NF-κB Pathway
por: Yang, Guang, et al.
Publicado: (2017)

KDELR2 knockdown synergizes with temozolomide to induce glioma cell apoptosis through the CHOP and JNK/p38 pathways
por: Zhang, Guofeng, et al.
Publicado: (2021)

Licochalcone B Induces ROS-Dependent Apoptosis in Oxaliplatin-Resistant Colorectal Cancer Cells via p38/JNK MAPK Signaling
por: Kwak, Ah-Won, et al.
Publicado: (2023)

Ethyl Acetate Extract of Asclepias curassavica Induced Apoptosis in Human Cancer Cells via Activating p38 and JNK MAPK Signaling Pathways
por: Zheng, Xi, et al.
Publicado: (2019)

Nonthermal Plasma Induces Apoptosis in ATC Cells: Involvement of JNK and p38 MAPK-Dependent ROS
por: Lee, Sei Young, et al.
Publicado: (2014)

S-Allylmercaptocysteine Targets Nrf2 in Osteoarthritis Treatment Through NOX4/NF-κB Pathway
por: Yang, Guang, et al.
Publicado: (2020)

Dexamethasone Induces Apoptosis of Nasal Polyp-Derived Tissue Cultures Through JNK and p38 MAPK Activation
por: Lee, Tae-Hoon, et al.
Publicado: (2014)

Nujiangexathone A, a Novel Compound Derived from Garcinia nujiangensis, Induces Caspase-Dependent Apoptosis in Cervical Cancer through the ROS/JNK Pathway
por: Zhang, Li, et al.
Publicado: (2016)

Neurotrophin3 promotes hepatocellular carcinoma apoptosis through the JNK and P38 MAPK pathways
por: Yang, Zhangshuo, et al.
Publicado: (2022)

H(2)S-induced pancreatic acinar cell apoptosis is mediated via JNK and p38 MAP kinase
por: Adhikari, Sharmila, et al.
Publicado: (2008)

High glucose promotes annulus fibrosus cell apoptosis through activating the JNK and p38 MAPK pathways
por: Shan, Lizhen, et al.
Publicado: (2019)

The Thioredoxin System Is Regulated by the ASK-1/JNK/p38/Survivin Pathway during Germ Cell Apoptosis
por: Al-Kandari, Nora, et al.
Publicado: (2019)

Irinotecan Induces Autophagy-Dependent Apoptosis and Positively Regulates ROS-Related JNK- and P38-MAPK Pathways in Gastric Cancer Cells
por: Zhu, Qingyun, et al.
Publicado: (2020)

Notoamide-type alkaloid induced apoptosis and autophagy via a P38/JNK signaling pathway in hepatocellular carcinoma cells
por: Hu, Likun, et al.
Publicado: (2019)

S100A16 suppresses the proliferation, migration and invasion of colorectal cancer cells in part via the JNK/p38 MAPK pathway
por: Ou, Shiyu, et al.
Publicado: (2021)

Roles of the MST1-JNK signaling pathway in apoptosis of colorectal cancer cells induced by Taurine
por: Liu, Zhuoqi, et al.
Publicado: (2018)

DHA ameliorates MeHg-induced PC12 cell apoptosis by inhibiting the ROS/JNK signaling pathway
por: Zhang, Hong, et al.
Publicado: (2021)

Vitamin K2 Induces Mitochondria-Related Apoptosis in Human Bladder Cancer Cells via ROS and JNK/p38 MAPK Signal Pathways
por: Duan, Fengsen, et al.
Publicado: (2016)

Phloretin induces apoptosis of non-small cell lung carcinoma A549 cells via JNK1/2 and p38 MAPK pathways
por: MIN, JIE, et al.
Publicado: (2015)

Activation of the JNK/SAPK and P38 Mitogen-Activated Protein Kinase Signaling Pathways Sensitize Tumor Cells to Cisplatin-Induced Apoptosis
por: Mansouri, Abdel, et al.
Publicado: (2001)

A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation
por: Liu, Xin, et al.
Publicado: (2016)

Oridonin induces apoptosis in HGC-27 cells by activating the JNK signaling pathway
por: Ren, Dong-Lin, et al.
Publicado: (2020)

Volatile compounds of fresh and processed garlic
por: Abe, Kazuki, et al.
Publicado: (2020)

Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK
por: Pereira, Lorena, et al.
Publicado: (2013)

Butylphthalide inhibits nerve cell apoptosis in cerebral infarction rats via the JNK/p38 MAPK signaling pathway
por: Bu, Xiangye, et al.
Publicado: (2021)

Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation
por: Zhang, Xiyu, et al.
Publicado: (2015)

Copper compound induces autophagy and apoptosis of glioma cells by reactive oxygen species and jnk activation
por: Trejo-Solís, Cristina, et al.
Publicado: (2012)

Ligustilide attenuates nitric oxide‐induced apoptosis in rat chondrocytes and cartilage degradation via inhibiting JNK and p38 MAPK pathways
por: Zhou, Yan, et al.
Publicado: (2019)

NADPH Oxidase 2-Derived Reactive Oxygen Species Mediate FFAs-Induced Dysfunction and Apoptosis of β-Cells via JNK, p38 MAPK and p53 Pathways
por: Yuan, Huiping, et al.
Publicado: (2010)

Garlic (Allium sativum)-derived SEVs inhibit cancer cell proliferation and induce caspase mediated apoptosis
por: Özkan, İrem, et al.
Publicado: (2021)

The natural compound Guttiferone F sensitizes prostate cancer to starvation induced apoptosis via calcium and JNK elevation
por: Li, Xin, et al.
Publicado: (2015)

SGLT1 Inhibition Attenuates Apoptosis in Diabetic Cardiomyopathy via the JNK and p38 Pathway
por: Lin, Na, et al.
Publicado: (2021)

Polyphyllin VI induces apoptosis and autophagy in human osteosarcoma cells by modulation of ROS/JNK activation
por: Yuan, Yong-Liang, et al.
Publicado: (2019)

Bioaccessibility of Bioactive Compounds of ‘Fresh Garlic’ and ‘Black Garlic’ through In Vitro Gastrointestinal Digestion
por: Moreno-Ortega, Alicia, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_26hlhsiif174blgesr8qhkgd4v