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Post-transplant lymphoproliferative disorder presenting as a tumor adjacent to the renal allograft: A case report and review of the literature
Post-transplant lymphoproliferative disorder (PTLD) is a potentially fatal complication of solid organ transplantation. The current report presents the case of a 42-year-old male who developed PTLD within the first year following renal transplantation. The disorder manifested as a tumor adjacent to...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214511/ https://www.ncbi.nlm.nih.gov/pubmed/25364435 http://dx.doi.org/10.3892/ol.2014.2586 |
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author | GAO, CHEN PENG, LONGKAI PENG, FENGHUA TUO, TING LI, DAIQIANG |
author_facet | GAO, CHEN PENG, LONGKAI PENG, FENGHUA TUO, TING LI, DAIQIANG |
author_sort | GAO, CHEN |
collection | PubMed |
description | Post-transplant lymphoproliferative disorder (PTLD) is a potentially fatal complication of solid organ transplantation. The current report presents the case of a 42-year-old male who developed PTLD within the first year following renal transplantation. The disorder manifested as a tumor adjacent to the lower pole of the renal allograft and resulted in urinary obstruction. Durable complete remission was achieved as a result of surgical resection followed by a reduction in immunosuppression and low-dose rituximab-based chemotherapy, indicating that this therapeutic strategy may be safe and effective for the treatment of specific cases of localized and resectable PTLD. |
format | Online Article Text |
id | pubmed-4214511 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-42145112014-10-31 Post-transplant lymphoproliferative disorder presenting as a tumor adjacent to the renal allograft: A case report and review of the literature GAO, CHEN PENG, LONGKAI PENG, FENGHUA TUO, TING LI, DAIQIANG Oncol Lett Articles Post-transplant lymphoproliferative disorder (PTLD) is a potentially fatal complication of solid organ transplantation. The current report presents the case of a 42-year-old male who developed PTLD within the first year following renal transplantation. The disorder manifested as a tumor adjacent to the lower pole of the renal allograft and resulted in urinary obstruction. Durable complete remission was achieved as a result of surgical resection followed by a reduction in immunosuppression and low-dose rituximab-based chemotherapy, indicating that this therapeutic strategy may be safe and effective for the treatment of specific cases of localized and resectable PTLD. D.A. Spandidos 2014-12 2014-10-02 /pmc/articles/PMC4214511/ /pubmed/25364435 http://dx.doi.org/10.3892/ol.2014.2586 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Articles GAO, CHEN PENG, LONGKAI PENG, FENGHUA TUO, TING LI, DAIQIANG Post-transplant lymphoproliferative disorder presenting as a tumor adjacent to the renal allograft: A case report and review of the literature |
title | Post-transplant lymphoproliferative disorder presenting as a tumor adjacent to the renal allograft: A case report and review of the literature |
title_full | Post-transplant lymphoproliferative disorder presenting as a tumor adjacent to the renal allograft: A case report and review of the literature |
title_fullStr | Post-transplant lymphoproliferative disorder presenting as a tumor adjacent to the renal allograft: A case report and review of the literature |
title_full_unstemmed | Post-transplant lymphoproliferative disorder presenting as a tumor adjacent to the renal allograft: A case report and review of the literature |
title_short | Post-transplant lymphoproliferative disorder presenting as a tumor adjacent to the renal allograft: A case report and review of the literature |
title_sort | post-transplant lymphoproliferative disorder presenting as a tumor adjacent to the renal allograft: a case report and review of the literature |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214511/ https://www.ncbi.nlm.nih.gov/pubmed/25364435 http://dx.doi.org/10.3892/ol.2014.2586 |
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