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Spinster Homolog 2 (Spns2) Deficiency Causes Early Onset Progressive Hearing Loss

Spinster homolog 2 (Spns2) acts as a Sphingosine-1-phosphate (S1P) transporter in zebrafish and mice, regulating heart development and lymphocyte trafficking respectively. S1P is a biologically active lysophospholipid with multiple roles in signalling. The mechanism of action of Spns2 is still elusi...

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Detalles Bibliográficos
Autores principales:	Chen, Jing, Ingham, Neil, Kelly, John, Jadeja, Shalini, Goulding, David, Pass, Johanna, Mahajan, Vinit B., Tsang, Stephen H., Nijnik, Anastasia, Jackson, Ian J., White, Jacqueline K., Forge, Andrew, Jagger, Daniel, Steel, Karen P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214598/ https://www.ncbi.nlm.nih.gov/pubmed/25356849 http://dx.doi.org/10.1371/journal.pgen.1004688

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