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Notch3 Interactome Analysis Identified WWP2 as a Negative Regulator of Notch3 Signaling in Ovarian Cancer

The Notch3 signaling pathway is thought to play a critical role in cancer development, as evidenced by the Notch3 amplification and rearrangement observed in human cancers. However, the molecular mechanism by which Notch3 signaling contributes to tumorigenesis is largely unknown. In an effort to ide...

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Detalles Bibliográficos
Autores principales:	Jung, Jin-Gyoung, Stoeck, Alexander, Guan, Bin, Wu, Ren-Chin, Zhu, Heng, Blackshaw, Seth, Shih, Ie-Ming, Wang, Tian-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214668/ https://www.ncbi.nlm.nih.gov/pubmed/25356737 http://dx.doi.org/10.1371/journal.pgen.1004751

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