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Genomic Instability and Radiation Risk in Molecular Pathways to Colon Cancer

Colon cancer is caused by multiple genomic alterations which lead to genomic instability (GI). GI appears in molecular pathways of microsatellite instability (MSI) and chromosomal instability (CIN) with clinically observed case shares of about 15–20% and 80–85%. Radiation enhances the colon cancer r...

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Detalles Bibliográficos
Autores principales:	Kaiser, Jan Christian, Meckbach, Reinhard, Jacob, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214691/ https://www.ncbi.nlm.nih.gov/pubmed/25356998 http://dx.doi.org/10.1371/journal.pone.0111024

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