Identification of a Novel Drug Lead That Inhibits HCV Infection and Cell-to-Cell Transmission by Targeting the HCV E2 Glycoprotein

Hepatitis C Virus (HCV) infects 200 million individuals worldwide. Although several FDA approved drugs targeting the HCV serine protease and polymerase have shown promising results, there is a need for better drugs that are effective in treating a broader range of HCV genotypes and subtypes without...

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Detalles Bibliográficos
Autores principales: Al Olaby, Reem R., Cocquerel, Laurence, Zemla, Adam, Saas, Laure, Dubuisson, Jean, Vielmetter, Jost, Marcotrigiano, Joseph, Khan, Abdul Ghafoor, Catalan, Felipe Vences, Perryman, Alexander L., Freundlich, Joel S., Forli, Stefano, Levy, Shoshana, Balhorn, Rod, Azzazy, Hassan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214736/
https://www.ncbi.nlm.nih.gov/pubmed/25357246
http://dx.doi.org/10.1371/journal.pone.0111333

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